“I think the Endocannabinoid System is the biggest breakthrough in Human History and most certainly modern medicine. The understanding of our human physiology and body is the greatest discovery of the century. It’s really sad that it’s received so little attention, and completely shocking to hear it not being taught in medical schools. We have this molecular signalling system within our body where the cells are talking to each other all the time.” — Anonymous Doctor.
A Cannabinoid is a bio-active compound [lipid/fat] that interacts in the bodies of all mammals. Throughout the brain and peripheral areas of the body, there are Cannabinoid receptors that modulate the release of neurotransmitters.
These primary receptors are named CB1 and CB2. The CB1 receptors exist primarily in the brain and nervous system while the CB2 receptors are found in immune cells, but this is only a starting point. The endocannabinoid system [ECS] is the largest neurotransmitter system in the human body.The medicinal components of the cannabis plant are called Phytocannabinoids (>130 identified), and the two main ‘endo,’ or ‘inner’ cannabinoids that the human body produces are Anandamide and 2-Arachidonoylglycerol [2-AG]. The biosynthesis and synergistic effect of cannabinoids create balance and equilibrium within the human body.
Today, the scientific reason for the ‘yin and yang’ referred to by Emperor Fu Hsi nearly five-thousands [5,000] years ago is becoming clear.
The ECS [endocannabinoid system] has deep phylogenetic roots and regulates many aspects of embryological development and homeostasis, including neuroprotection and neural plasticity, immunity and inflammation, apoptosis and carcinogenesis, pain and emotional memory, regulating hunger, feeding, and metabolism.”
“Human breast milk is a source of Endocannabinoids — these compounds act as Neuromodulators that stimulate the suckling process by activating oral-motor musculature, which helps teach children to eat…”
THC - Tetrahydrocannabinol
THC, or Tetrahydrocannabinol, is the chemical responsible for most of marijuana's psychological effects. It acts much like the cannabinoid chemicals made naturally by the body, according to the National Institute on Drug Abuse (NIDA). Cannabinoid receptors are concentrated in certain areas of the brain associated with thinking, memory, pleasure,coordination and time perception. THC attaches to these receptors and activates them and affects a person's memory, pleasure, movements, thinking, concentration, coordination, and sensory and time perception, according to NIDA. THC is one of many compounds found in the resin secreted by glands of the marijuana plant. More of these glands are found around the reproductive organs of the plant than on any other area of the plant. Other compounds unique to marijuana, called cannabinoids, are present in this resin. One cannabinoid, CBD is non-psychoactive, according to the National Center for Biotechnology Information, and actually blocks the high associated with THC.
According to the National Cancer Institute, marijuana has been used for medicinal purposes for more than 3,000 years. As of early 2017, more than half of the United States has legalised the use of medicinal marijuana. Several states have also legalised the drug for recreational use, as well.
THC can be extracted from marijuana, or synthesised, as is the case for the FDA-approved drug dronabinol. Dronabinol is used to treat or prevent the nausea and vomiting associated with cancer medicines and to increase the appetites of people with AIDS, according to the U.S. National Library of Medicine. It is a light yellow resinous oil.
Other studies are showing more evidence that, when used properly, THC has many additional medical benefits. For example, THC may be able to improve memory when taken in small doses, according to a 2016 study on Mice!? (Poor Animals) marajiuana cannabis clinic